This option accounts for variation in the total shedding load
per case by modeling individual shedding loads as Gamma distributed with
mean equal to the average load_per_case
and a coefficient of variation to
be estimated.
Usage
load_variation_estimate(
cv_prior_mu = 1,
cv_prior_sigma = 0,
modeldata = modeldata_init()
)
Arguments
- cv_prior_mu
Mean of the truncated normal prior for the coefficient of individual-level variation. Default is a CV of 1, which means that approximately 60% of individuals shed less than the mean, and approximately 10% of individuals shed less than 10% of the mean.
- cv_prior_sigma
Standard deviation of the truncated normal prior for the coefficient of individual-level variation. If this is set to zero, the coefficient of variation is fixed to the mean.
- modeldata
A
modeldata
object to which the above model specifications should be added. Default is an empty model given bymodeldata_init()
. Can also be an already partly specified model returned by otherEpiSewer
modeling functions.
Value
A modeldata
object containing data and specifications of the model
to be fitted. Can be passed on to other EpiSewer
modeling functions to
add further data and model specifications.
The modeldata
object also includes information about parameter
initialization (init
), meta data (.metainfo
), and checks to be
performed before model fitting (.checks
).
Details
Note that measurement noise and individual-level load variation might not be jointly identifiable. This is why the coefficient of variation of the individual-level load is fixed by default.
Also note that the accuracy of the variation model depends on the
estimated number of cases to be on the right scale (which in turn depends
on the assumed load_per_case
to be roughly correct). This is because in
the variation model, the population-level coefficient of variation (CV) of
shedding loads is proportional to the individual-level CV divided by the
square root of the number of cases. If for example the assumed
load_per_case
is too small, the number of cases will be overestimated,
which has effects in two directions:
the individual-level CV will be overestimated (especially if the prior on the individual-level CV is weak)
the population-level CV will be underestimated (especially if the prior on the individual-level CV is strong)
See also
Other load variation models:
load_variation_none()