This option drops all zero measurements from the likelihood and does not explicitly model a limit of detection.
Usage
LOD_none(modeldata = modeldata_init())Arguments
- modeldata
A
modeldataobject to which the above model specifications should be added. Default is an empty model given bymodeldata_init(). Can also be an already partly specified model returned by otherEpiSewermodeling functions.
Value
A modeldata object containing data and specifications of the model
to be fitted. Can be passed on to other EpiSewer modeling functions to
add further data and model specifications.
The modeldata object also includes information about parameter
initialization (.init), meta data (.metainfo), and checks to be
performed before model fitting (.checks).
Details
Dropping zero measurements implicitly assumes that any level of concentration can theoretically lead to a zero measurement. Since the corresponding observations are dropped, this will discard information, but not bias estimates.
See also
Other LOD models:
LOD_assume(),
LOD_estimate_dPCR()